ea0099oc11.2 | Oral Communications 11: Adrenal and Cardiovascular Endocrinology | Part II | ECE2024
Cozma Diana
, Siatra Panagiota
, Oikonomakos Ioannis
, Friedrich Ulrike
, Bornstein Stefan
, Andoniadou Cynthia
, Steenblock Charlotte
Metabolic syndrome is characterized by the hyperactivation of the hypothalamic-pituitary-adrenal (HPA) axis, leading to increased steroidogenesis and altered cortisol secretion. The molecular signaling mechanisms underlying HPA axis alterations in metabolic diseases remain poorly understood. In this study, our objective is to investigate how changes in signaling molecules within both plasma and adipose tissue contribute to the regulation of adrenal steroidogenesis in metabolic...